Zobrazení zdroje stránky Nicholsonconradsen5790

Other secondary outcomes (quality of life, empowerment, negative symptoms) showed no significant effects. CONCLUSIONS As a nursing intervention, CAT leads to maintained improvements in daily functioning, and may improve executive functioning and visual attention in people with SMI in need of longer-term intensive psychiatric care. Given the paucity of evidence-based interventions in this population, CAT can become a valuable addition to recovery-oriented care. © The Author(s) 2020. Published by Oxford University Press on behalf of the Maryland Psychiatric Research Center.Radiation protection factor (RPF) values are relevant to various US defense and civil support organizations. An equation was developed to quantify the angular-dependent protection of a shielding configuration in the presence of a mono-energetic radiation field. Values of ambient dose equivalent, H*(10), were computed with version 6.1 of the Monte Carlo N-Particle Code (MCNP6.1) for more than 70 distinct, mono-energetic, planar photon and neutron fields using both the kerma approximation and energy deposition from primary and secondary radiations. The two computational approaches were compared, and the MCNP6.1 models were then modified to simulate the same radiation fields and compute values of directional dose equivalent, H'(10,α), in a tissue sphere centered inside a surrogate vehicle for 13 angles of incidence. Values of H*(10) and H'(10,α) were recast as energy- and angular-dependent RPF values for the incident field-shielding geometries and tabulated. Examples of implementation are provided, and limitations are discussed. Published by Oxford University Press 2020.New technique is trending in spatially fractionated radiotherapy with protons to utilize the spot scanning together with a physical collimator to obtain minibeams. The primary goal of this study is to quantify ambient neutron dose equivalent ($H^\ast (10)$) due to the secondary neutrons when physical collimator is used to achieve desired minibeams. The $H^\ast (10)$ per treatment proton dose (D) was assessed using Monte Carlo code TOPAS and measured using WENDI-II detector at different angles (135, 180, 225 and 270 degrees) and distances (11&nbsp;cm, 58 and 105&nbsp;cm) from the phantom for two cases with and without physical collimation. Without collimation $\fracH^\ast (10)D$ varied from 0.0013 to 0.242&nbsp;mSv/Gy. With collimation $\fracH^\ast (10)D$ varied from 0.017 to 3.23&nbsp;mSv/Gy. Results show that the secondary neutron dose will increase tenfold when the physical collimator is used. Regardless, it will be low and comparable to the neutron dose produced by conventional passive-scattered proton beams. © The Author(s) 2020. Published by Oxford University Press. All rights reserved. For Permissions, please email journals.permissions@oup.com.BACKGROUND Autologous fat grafting is a common procedure to improve tissue deficiencies. However, the survival rate of fat grafting is unpredictable. Thymosin beta 4(Tß4), a multifunctional 43 amino acids, is effective in angiogenesis, inhibiting apoptosis and inflammation. OBJECTIVES The authors initially investigated the potential effect of Tß4 in fat grafting. METHODS Free adipose granules premixed exogenous Tß4 were transplanted into the rabbit ears. Rabbits were randomly into three groups group A, Tß4 5μg/ml; group B, Tß4 10μg/ml; group C, phosphate-buffered saline buffer as a blank control. The fat grafts were subjected to magnetic resonance imaging at 2, 4, and 12 weeks in vivo. Each harvested graft was analyzed at 3 time points after transplantation. RESULTS The fat grafts in the Tß4-treated groups showed better volume and weight retention, greater adipose tissue integrity, adipocyte viability, and angiogenesis. The results of DCE-MRI also showed that the experimental groups also increased microcirculation perfusion of the grafts. CONCLUSIONS The study proved that thymosin beta4 could improve adipose tissue survival and neovascularization. It may be useful for fat grafting as a potential protective reagent. © 2020 The Aesthetic Society. Reprints and permission journals.permissions@oup.com.BACKGROUND Classic nasal hump reduction based on partial resection of the cartilage and bones in the nose may lead to dorsum deformities such as an inverted V deformity, irregularities, and open roof. Techniques that preserve the nasal dorsum (namely the push-down and let-down) avoid these problems, but may not be always indicated for very large, broad, or deviated noses, while cartilaginous push-down is also indicated for large and deviated humps. Because only the cartilaginous portion of the hump is preserved in the cartilaginous push-down, a rough area may remain where the bony portion is resected. OBJECTIVES Here we present a variation of the cartilaginous push-down technique which includes a bony cap to preserve the smoothness of the keystone area during nasal hump treatment. METHODS Forty-eight consecutive patients with indication for nasal hump treatment that underwent cartilaginous push-down procedures with bony cap preservation between August 2018 and October 2019 were studied. RESULTS We observed related complications in 2 patients (4.2%); in one patient (2.1%) the bony cap was lost during the rasping of the nasal bones and the surgery was altered to utilize only the cartilaginous push-down. Another patient (2.1%) experienced a mild hump recurrence during the early weeks following the procedure. All of the remaining patients had their nasal humps treated adequately. CONCLUSIONS In this study, the nasal hump was adequately corrected in most patients (95.8%). Preserving the bony cap while performing the cartilaginous push-down may prevent complications related to the osseous resection of the keystone area. © 2020 The Aesthetic Society.OBJECTIVES Shift work with circadian disruption is a suspected human carcinogen. Additional population-representative human studies are needed and large population-based linkage cohorts have been explored as an option for surveillance shift work and cancer risk. This study uses a surveillance linkage cohort and job-exposure matrix to test relationships. METHODS We estimated associations between shift work and breast, ovarian, and prostate cancer using the population-based Canadian Census Health and Environment Cohort (CanCHEC), linking the 1991 Canadian census to national cancer registry and mortality databases. [https://www.selleckchem.com/products/sel120.html SEL120] Prevalence estimates from population labour survey data were used to estimate and assign probability of night, rotating, or evening shifts by occupation and industry. Cohort members were assigned to high (&gt;50%), medium (&gt;25 to 50%), low (&gt;5 to 25%), or no ( less then 5%) probability of exposure categories. Cox proportional hazards modelling was used to estimate associations between shift work exposure and incidence of prostate cancer in men and ovarian and breast cancer in women.