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were isolated, which can be regarded as the circulation of hospital strains outside the medical institutions.<br /><br /> The aim To analyze the epidemiological data and clinical course of pneumonia as a complication of influenza in the Poltava region, depending on the etiological agent.<br /><br /> Materials and methods We have analysed the data of the official reporting documentation provided by the State Institution "Poltava Regional Laboratory Center of the Ministry of Health of Ukraine" and the chart of patients with a laboratory confirmed diagnosis of influenza who were in inpatient treatment at the Poltava Regional Clinical Infectious Hospital (PRCIH) in 2016-2018 years. In more detail, we examined 95 patients with pneumonia, which complicated the course of the flu. There were 43 (45.26%) female patients, - 52 (54.74%) male patients, aged 18 to 80 years.<br /><br /> Results Studies have shown that despite a decrease in the incidence of influenza in recent years, the incidence of pneumonia, which complicated the course of the flu, remained consistently high (19.7% - 20.8%) with bacteriological isolation of S.pneumoniae (22.11%), S.aureus (1sed by S.pneumoniae, S.aureus, Haemophilus influenza and E.coli. Pneumonia caused by S.pneumoniae and S.aureus, were characterizedthe most severe course; however, a severe course with the formation of abscesses in the lung tissue was observed only in the group of S.aureus.<br /><br /> The aim The aim is to study the effect of β-ABs in patients with LT3 S on the course of HF.<br /><br /> Materials and methods 354 patients with HF on a background of post-infarction cardiosclerosis were included in the 2-yeared follow-up study. LT3 S was diagnosed at 89 (25.1%) patients. [https://www.selleckchem.com/products/rimiducid-ap1903.html selleck] The levels of thyroid-stimulating hormone, free T3f and T4f, and reversible T3 were determined. The echocardioscopy was performed.<br /><br /> Results Patients with HF in combination with LT3 S have a heavier functional class by NYHA, greater dilatation of the left heart cavities, less myocardial contractility, a higher frequency of atrial fibrillation and re-hospitalization. The use of β-ABs in patients with HF without LT3 S leads to a likely decrease in hospitalization frequency, while in patients with LT3 S it has an opposite effect. The frequency of rehospitalization increases with an excess of β-ABs dose &gt; 5 mg (equivalent to bisoprolol). At these patients a decrease in serum T3 level and negative dynamics of parameters of intracardiac hemodynamics are observed.<br /><br /> Conclusions The use of β-ABs in patients with LT3 S leads to an increase in re-hospitalization at a dose over 5.0 mg (equivalent to bisoprolol). In these patients there is a decrease in serum T3, an increase in T4 level; and the ejection fraction decrease; and heart cavities size increase.<br /><br />Conclusions The use of β-ABs in patients with LT3 S leads to an increase in re-hospitalization at a dose over 5.0 mg (equivalent to bisoprolol). In these patients there is a decrease in serum T3, an increase in T4 level; and the ejection fraction decrease; and heart cavities size increase.<br /><br /> The aim To perform a retrospective analysis of leptospirosis morbidity in Ivano-Frankivsk region, to give the etiological characteristics of leptospirosis according to clinicallaboratory parameters, to determine the peculiarities of the course, prognostic features.<br /><br /> Materials and methods Data of the State Enterprise "Ivano-Frankivsk Regional Laboratory Center of the Ministry of Health of Ukraine", reports and abstracts of medical records of the Regional Clinical Infectious Diseases Hospital for 2009-2018 were used. Clinical observation of patients, analysis of general-clinical, biochemical, and serological indices were carried out.<br /><br /> Results The leptospirosis morbidity in Ivano-Frankivsk region during 2009-2018 was higher than in general in Ukraine. Activation of foci of leptospirosis L. pomona and grippotyphosa in 2009-2013, decrease of L. grippotyphosa and increase of L. pomona foci and "new" L. autumnalis, australis, bataviae, cynopteri in 2014-2018 were noted. The emergence of leptospirosis L. autumnalecreased (2.1%), L. bataviae and cynopteri, autumnalis increased (by 8.5%). Seasonality is shifted in the autumn-winter period (November-February) (L. grippotyphosa, australis, pomona, canicola). According to forecasts, leptospirosis induced by L. autumnalis was most adverse. Leptospiroses of serogroups L. australis, bataviae, cynopteri had a mild course, there were fewer complications.<br /><br /> The aim assessment of the patients with paranoid schizophrenia adaptive personal potential.<br /><br /> Materials and methods Clinical-anamnestic method, questionnaires for determining "structural ego-states" by J. Hey, of the "drivers" by M. Cox, of the "personal adaptations" by Joines, for determining the "crisis moments of development" by J.I. Clark, statistical analysis of the results data. 164 patients with a newly diagnosed and episodic paranoid schizophrenia took part in this study.<br /><br /> Results "Passive behavior" serves as a typical door for contact by 88% of the patients. According to the methodologies of determination of the "drivers" the following results were received "make the others happy" - 28%, "be strong" - 76%, "be perfect" - 65%, "make efforts" - 5% "hurry up" - 15%; of "crisis moments in development" determination, 61% were determined as "stuck" in the 1st stage of the development. By 74%, there was a "script prohibition", "do not be close." By 72% there was a "prohibition" "do not have feelings". The prevailing combinations of the "personal adaptations" were "schizoid" (92%) and "paranoid" (81%).<br /><br /> Conclusions schizophrenia can be viewed as a defensive reaction. The "ego- states of the controlling parent" and "adaptive child" dominate. The dominant "drivers" are "make the others happy" and "be strong." Typical "script prohibitions" are "do not be close," "do not feel," "do not think" and "do not be healthy." The typical "personal adaptations" of the patients are "schizoid" and "paranoic".<br /><br />Conclusions schizophrenia can be viewed as a defensive reaction. The "ego- states of the controlling parent" and "adaptive child" dominate. The dominant "drivers" are "make the others happy" and "be strong." Typical "script prohibitions" are "do not be close," "do not feel," "do not think" and "do not be healthy." The typical "personal adaptations" of the patients are "schizoid" and "paranoic".