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Novel coronavirus 2019 (COVID-19) has been one of the largest and most devastating global pandemics of our time. There have been several complications of this disease that have also proven to be debilitating and deadly. While primarily affecting the respiratory system, some cases presented with uncommon complications such as pneumopericardium and spontaneous pneumothorax. We present a case of an elderly female diagnosed with COVID-19 found to have both spontaneous pneumothorax and pneumopericardium. She had a complicated hospital course and ultimately succumbed to her illness. While the pathogenesis of these conditions is not yet fully understood, further studies are needed to help clinicians develop treatment and prevention strategies to improve patient outcomes.Pediatric morbidity and mortality associated with methadone poisoning have been rising over the years. In this report, we discuss a case of a four-year-old boy who presented with respiratory distress and a depressed level of consciousness. A urine drug testing was performed given the miosis along with the depressed level of consciousness; the test was found to be positive for methadone, and no other cause of drowsiness was identified. This report highlights the importance of urine drug testing in pediatric patients presenting with a depressed level of consciousness.The mastoid process is a conical projection from the undersurface of the temporal bone. Examination of skeletal remains by anthropologists requires sex determination. The present study proposes to determine sex from morphometry of the mastoid process. The study was conducted on 300 dried skulls with the help of a digital vernier caliper. Discriminant functional analysis was performed. The parameters measured were the mastoid triangle, which is formed by specific points the porion, mastoidale, and asterion, and the linear distances between them. All parameters were higher in male skulls with a high level of significance. The area of the mastoid triangle proved to be the best parameter for sex discrimination.Artificial intelligence (AI) has a considerable present and future influence on healthcare. Nurses, representing the largest proportion of healthcare workers, are set to immensely benefit from this technology. However, the overall adoption of new technologies by nurses is quite slow, and the use of AI in nursing is considered to be in its infancy. The current literature on AI in nursing lacks conceptual clarity and consensus, which is affecting clinical practice, research activities, and theory development. Therefore, to set the foundations for nursing AI knowledge development, the purpose of this concept analysis is to clarify the conceptual components of AI in nursing and to determine its conceptual maturity. A concept analysis following Morse's approach was conducted, which examined definitions, characteristics, preconditions, outcomes, and boundaries on the state of AI in nursing. A total of 18 quantitative, qualitative, mixed-methods, and reviews related to AI in nursing were retrieved from the CINAHL and EMBASE databases using a Boolean search. Presently, the concept of AI in nursing is immature. The characteristics and preconditions of the use of AI in nursing are mixed between and within each other. The preconditions and outcomes on the use of AI in nursing are diverse and indiscriminately reported. As for boundaries, they can be more distinguished between robots, sensors, and clinical decision support systems, but these lines can become more blurred in the future. As of 2021, the use of AI in nursing holds much promise for the profession, but conceptual and theoretical issues remain.Introduction Coronary artery calcium (CAC) scoring is used as a screening tool for patients with intermediate 10-year arteriosclerotic cardiovascular disease (ASCVD) risk. Results obtained on non-contrast non-gated chest CT (ngCCT) correlate well to those obtained on gated CTs. This paper aims to determine how the routine reporting of CAC scores on ngCCT scans with ASCVD risk of less than 12.5% would change statin management. Methods Data of all patients scanned on a single CT scanner during a four-month window were reviewed. A total of 521 eligible scans were identified. After removing duplicate scans and scans from patients who were not in the age range of 40-75 years, 370 scans remained. Patients were excluded if they had documented ASCVD, type 2 diabetes mellitus, or low-density lipoprotein (LDL) &gt; 190 mg/dL, or if they had ASCVD risk of greater than 12.5%. [https://www.selleckchem.com/products/kpt-9274.html Selleck ATG-019] Ultimately, 36 scans were included in the study. Results Of the 36 patients who qualified, 10 were low-risk (ASCVD risk less then 5%), 13 were intermediate-risk (ASCVD risk 5-7.5%), and 13 were high-risk (ASCVD risk 7.5%-12.5%). A CAC score of 300 was used as a cutoff for recommending prescribing statins and 0 was used as a cutoff for recommending de-prescribing statins. In 63% of patients (23/36), CAC scoring altered statin recommendations. This included 11/13 (85%) intermediate-risk patients, 6/13 (46%) high-risk patients, and 6/10 (60%) low-risk patients. Conclusions Reporting CAC on ngCCTs obtained for other reasons can significantly impact statin prescribing practices. This may improve cost, patient satisfaction, and patient safety.A few individuals are believed to have developed immune thrombocytopenia (ITP) following the administration of the coronavirus disease 2019 (COVID-19) vaccine. This phenomenon has been reported in a few case reports and also in some recent news articles. In this report, we discuss a case of a 54-year-old Caucasian female who presented to the emergency room with life-threatening thrombocytopenia in the setting of de novo ITP following COVID-19 vaccine administration. Due to the relapsing nature of ITP, it is unclear if the patient has achieved complete remission of the disease.<br /><br /> We have previously performed an analysis of the cold-responsive transcriptome in the mature leaves of tiger lily (<br /><br /> ) by gene co-expression network identification. The results has revealed that a <br /><br /> gene, notated as encoding zinc finger homeodomain protein, may play an essential regulating role in tiger lily response to cold stress.<br /><br /> A further investigation of the <br /><br /> gene (termed as <br /><br /> ) responding to osmotic stresses, including cold, salt, water stresses, and abscisic acid (ABA) was performed in this study. Based on the transcriptome sequences, the coding region and 5' promoter region of <br /><br /> were cloned from mature tiger lily leaves. Stress response analysis was performed under continuous 4 °C, NaCl, PEG, and ABA treatments. Functional characterization of <br /><br /> was conducted in transgenic <br /><br /> , tobacco, and yeast.<br /><br /> encodes a nuclear-localized protein consisting of 180 amino acids. The N-terminal region of LlZFHD4 has transcriptional activation activity in yeast. The 4 °C, NaCl, PEG, and ABA treatments induced the expression of <br /><br /> .