Zobrazení zdroje stránky Koefoedmaldonado1664

0% (Q1=15.8; Q3=38.6). Fat intake was positively associated with BMI, insulin, and HOMA-IR index, while carbohydrate consumption was related to these same factors, although negatively in tight models.<br /><br /> Schoolchildren in this study had an inadequate protein, carbohydrate, and fiber intake. The results suggest a significant positive and negative relationship between the consumption of both fat and carbohydrates and cardiometabolic risk factors such as BMI, insulin levels, and HOMA-IR.<br /><br />Schoolchildren in this study had an inadequate protein, carbohydrate, and fiber intake. The results suggest a significant positive and negative relationship between the consumption of both fat and carbohydrates and cardiometabolic risk factors such as BMI, insulin levels, and HOMA-IR.<br /><br /> Accurate management of metabolic decompensation in maple syrup urine disease (MSUD) has a crucial role, as acute attacks can cause neurological sequels and can be life threatening. [https://www.selleckchem.com/products/Tigecycline.html Tigecycline] Here, we aimed to evaluate effect of sodium phenylbutyrate (NaPBA) in acute management of MSUD attacks.<br /><br /> Episodes with an initial plasma leucine (Leu) level above 750µmoL/L and that require hospitalization due to clinical findings of Leu neurotoxicity and/or feeding difficulties were included to the study. Patients who had no molecular diagnosis and a regular follow-up were excluded. Clinical findings, laboratory results and therapy responses were reviewed, retrospectively.<br /><br /> Ten patients who experienced 19 distinct episodes of MSUD attacks were enrolled. Initial median Leu level was 901.67 (range 756-1989.11) and 33.9µmoL/L (range 7.91-347.3µmoL/L) at the end of therapy. None of our patients underwent extracorporeal toxin removal during the course of attack. In patients with serial plasma quantitative amino acid sampling, mean dynamic instability.<br /><br /> Pediatric pheochromocytoma and paraganglioma (PPGL) are rare tumors with limited data on the diagnostic performance of <br /><br /> Ga-DOTA(0)-Tyr(3)-octreotate positron emission tomography-computed tomography (<br /><br /> Ga-DOTATATE PET/CT). We have described our experience of <br /><br /> Ga-DOTATATE PET/CT in overall and von Hippel Lindau (VHL)-associated pediatric PPGL and compared its sensitivity with that of <br /><br /> I-meta-iodobenzyl-guanidine (<br /><br /> I-MIBG), <br /><br /> F-fluorodeoxyglucose PET/CT (<br /><br /> F-FDG PET/CT), and contrast-enhanced CT (CECT).<br /><br /> Retrospective evaluation of consecutive PPGL patients (age≤20 years), who had undergone at least one functional imaging [<br /><br /> I-MIBG, <br /><br /> F-FDG PET/CT, and/or <br /><br /> Ga-DOTATATE PET/CT], was done. Composite of anatomical and all the performed functional imaging scans, image comparator (IC), was considered as the gold standard for sensitivity analysis.<br /><br /> In a cohort of 32 patients (16 males, age at diagnosis 16.4±2.68 years), lesion-wise sensitivity of <br /><br /> Ga-DOTATATE PET/CT (95%) was higher than that of both<br /><br /> F-FDG-Pllance in VHL.<br /><br /> In 2011, we described 104 girls who were diagnosed as early puberty (EP) during 2003-2005. In 2019-2020, the former EP women had been followed up 14 years after attaining their final height.<br /><br /> To determine the reproductive function and metabolic profiles of former EP women.<br /><br /> Fifty-seven former EP women were evaluated for reproductive function and examined for health status. Blood samples were obtained for metabolic profilesof glucose, lipids and insulin, and testosterone levels.<br /><br /> In 2020, the average age of the study women was 22.9±1.7 years. The average height was 156.7±5.6cm. The average weight had increased from 52.5±7.8kg in 2011 to 58.5±11.1kg in 2020 and average body mass index (BMI) from 21.4±2.9 to 23.8±4.0kg/m<br /><br /> . Obesity (BMI&gt;25kg/m<br /><br /> ) was found in 8.8% (five participants) in 2011 and had increased to 22.8% (13 participants) in 2020. Most participants (79%) had regular menstrual cycle. Of the 17 married women, 4 (23.5%) had 1-2 children. Dividing the participants into obese and nonobese groups, the average fasting plasma glucose, lipid profiles, and testosterone levels were similar in both groups. However, the average systolic blood pressure and the serum insulin levels and HOMA-IR assessments were significantly higher in the obese group than in the nonobese group.<br /><br /> The former EP women had normal menstruation and reproductive function. The former EP women with average BMI at the follow-up had normal metabolic profiles while those who later became obese had significantly higher systolic blood pressure, serum insulin, and HOMA-IR assessments.<br /><br />The former EP women had normal menstruation and reproductive function. The former EP women with average BMI at the follow-up had normal metabolic profiles while those who later became obese had significantly higher systolic blood pressure, serum insulin, and HOMA-IR assessments.<br /><br /> Children and their mothers, who are usually the primary caregivers, are likely to be distressed due to type 1 diabetes (T1DM).<br /><br /> (1) To assess diabetes-specific distress (DD) perceived by children and adolescents with T1DM and their mothers and association of distress between children and mothers. (2) To study the association of diabetes distress with glycemic control and disease duration.<br /><br /> Children and adolescents with T1DM over eight years and their mothers.<br /><br /> Clinical data were recorded. DD was assessed by Problem Associated in Diabetes-Pediatric (PAID-Peds) (range 0-80) and Problem Associated in Diabetes-Parents Revised (PAID-PR) (range 0-72) questionnaires (higher scores indicate higher distress); administered to children and mothers, respectively. Sub-dimensions in questionnaires included diabetes-related emotional problems, and treatment-, food-, and social support-related problems. Correlation analysis (Spearman's) was performed, and a paired <br /><br /> -test was used to compare PAID-Peds and PAID-PR (SPSS 25).<br /><br /> Mean PAID-Peds and PAID-PR scores in 67 children and mothers were 24.4±18.1 and 31.9±21.5, respectively (p=0.009), and a significant correlation was noted between their scores (R=0.45, p=0.001). PAID-Peds score was positively associated with HbA1c (R=0.25, p=0.04). Diabetes-related emotional problems of mothers and children (R=0.38, p=0.003), treatment problems (R=0.5, p=0.001), and food problems (R=0.24, p=0.05) correlated positively. Subdimension scores were significantly different in children and mothers except in the social support domain.<br /><br /> DD was higher in mothers than children; higher distress in children was associated with poor metabolic control. Evaluation of DD needs to be performed in children with T1DM.<br /><br />DD was higher in mothers than children; higher distress in children was associated with poor metabolic control. Evaluation of DD needs to be performed in children with T1DM.