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BACKGROUND Various treatment modalities have been applied to treat striae alba (SA) with low satisfaction rate. Fractional microneedling radiofrequency (FMR) provides deep dermal coagulation, thereby inducing collagen synthesis and tissue tightening. The addition of platelet-derived lyophilized growth factors may add to the effect of FMR. OBJECTIVES To evaluate and compare the efficacy and safety of FMR alone or combined with lyophilized growth factors in the treatment of SA. METHODS In this left-right comparative study, 25 patients suffering from SA on the abdomen received four sessions of FMR with lyophilized growth factors on one side and with saline (as placebo) on the other side at 4&nbsp;weeks interval. Photographic and biopsy documentation of the progress of the SA was carried out before the start of the treatment and 4&nbsp;weeks after the last session. Calculation of the width of SA before treatment and after 4 sessions was done by Adobe Photoshop CS6. RESULTS There was a significant improvement in SA width after treatment in both the lyophilized growth factors (P&nbsp;=&nbsp; less then .0001) and placebo sides (P&nbsp;=&nbsp; less then .0001), the lyophilized growth factors being superior (P&nbsp;=&nbsp;.002). Patient satisfaction was more on the lyophilized growth factors (LGF) side (P&nbsp;=&nbsp;.034). Erythema and hyperpigmentation were less on the lyophilized growth factors side. Histopathologically, both showed improvement with no difference between LGF and placebo (epidermal thickness (P&nbsp;=&nbsp;.456), collagen content (P&nbsp;=&nbsp;.297), elastin content (P&nbsp;=&nbsp;.239)). CONCLUSION The combination of FMR and lyophilized growth factors improves SA outcome. © 2020 Wiley Periodicals, Inc.While some progress has been made in addressing chronic homelessness through supportive models, a comprehensive solution for housing loss must include prevention. The purpose of this article is twofold to conduct a review of the literature on the domains of the Framework for Homelessness Prevention; and to use literature on the concept of quaternary prevention, preventing the harms of service provision, to theorise an additional domain. The Framework for Homelessness Prevention draws upon theory from public health exploring primary, secondary and tertiary prevention, and also integrates primordial prevention. This leads to a typology of homelessness prevention that incorporates the following five domains (a) Structural prevention; (b) Systems prevention; (c) Early intervention; (d) Eviction prevention; and (e) Housing stability. By systematically reviewing the literature we build out the evidence-base supporting these domains. The team used research databases, internet searches and retrospective reference list reviews to identify high-quality journal articles on prevention, which were then sorted by level of prevention. Through this process, we evolved our thinking on the Framework in considering that quaternary prevention was not initially included. Therefore, we explored the literature related to quaternary prevention in the context of homelessness and offer a sixth domain for the Framework Empowerment. Ultimately, a comprehensive Framework for Homelessness Prevention will support communities and governments to more effectively prevent homelessness through upstream approaches. © 2020 John Wiley &amp; Sons Ltd.AIM Although alveolar ridge preservation (ARP) procedures appear to limit bone resorption after dental extraction, long-term outcomes remain limited. The objective of this prospective case series was to evaluate the long-term hard and soft tissue changes after ARP procedure in the aesthetic area, using deproteinized bovine bone mineral (DBBM) and saddle connective tissue graft. MATERIALS AND METHODS Fifteen patients were subjected to ARP and impressions and CT scans were taken at baseline and 3 months. After 5 to 7 years, a secondary long-term clinical and radiological analysis was carried out. Horizontal alveolar bone changes, soft tissue profiles and implant outcomes were assessed. RESULTS Although a limited hard and soft tissue remodeling occurred during the first 3 months after ARP, from 3 months to the long-term evaluation, the alveolar bone dimensions remained stable and the soft tissue profiles significantly increased, in the more cervical levels. The implant survival rate after 5 to 7 years yielded 100% and peri-implant bone levels and soft tissue health were good. CONCLUSION Within the limits of the study, the present data confirms the long-term effectiveness of ARP using DBBM and a saddle connective tissue graft offering stable hard and soft tissue conditions up to 5 to 7 years. © 2020 Wiley Periodicals LLC.BACKGROUND Home-based voluntary human immunodeficiency virus (HIV) counseling and testing (HBVCT) plays a significant role in reducing HIV-related risk-taking behaviors. Adopting evidence-based interventions is essential, but few conceptual models exist to guide the development, implementation, and evaluation of these interventions. AIMS Our proposed model for evidence translation based on evidence review describes the implementation process of HBVCT in the community. MATERIALS AND METHODS Our study adopted the translating research into practice model, which incorporates information needs about the implementation, planning, and execution required for consideration by clinicians. Thirteen systematic reviews published in the English language from January 1, 2000 to February 9, 2020 were retrieved and reviewed from four electronic databases and journals, including EMBASE, PubMed, JBI Database of Systematic Reviews and Implementation Reports, and Cochrane Library. RESULTS The analysis of the review papers based on the phenomenon of interest, results, and the population revealed some distinctions in the number of socioecological levels used by this evidence synthesis. These levels of factors include individual, interpersonal, organizational, community, and public policies. HBVCT is an essential component of HIV prevention programs and a critical entry point for adequate care and treatment. [https://www.selleckchem.com/products/Nafamostat-mesylate.html learn more] DISCUSSION This collaborative model demonstrates the application of research to a real-world health care setting. © 2020 Wiley Periodicals, Inc.