Zobrazení zdroje stránky Gammelgaardpolat2905

49 ± 16 years, p = 0.008, 100% vs. 40%, p = 0.003 and 78% vs. 25%, p = 0.014, respectively). In patients with LVEF ≤ 35%, LGE of any type, diagnosed in 86.2% of patients, was associated with CAD (68% vs. 0%, p = 0.02), while only trends were observed for its association with older age and previous MI (p = 0.08 and p = 0.12, respectively). CONCLUSIONS Among HF patients with LVEF ≤ 35%, clinical factors including older age, CAD, and previous MI are associated with transmural LGE in the posterolateral wall, while CAD is associated with LGE. This data may have potential implications for planning ICD and CRT placement procedures.BACKGROUND Global longitudinal strain (GLS) based on two-dimensional speckle-tracking echocardiography (2D-STE) might better reflect left ventricular (LV) contractile performance than conventional parameters. Recently, left atrial (LA) strain has been used as a more accurate alternative to assessing LA performance. The aim in this study was to assess the clinical prognostic value of left ventricular GLS (LV GLS) and peak atrial longitudinal strain (PALS) in patients after ST-segment-elevation myocardial infarction (STEMI). METHODS The study enrolled 199 patients who underwent primary percutaneous coronary intervention (pPCI) for first STEMI. Conventional and 2D-STE were performed within 48 h after pPCI. LV GLS and PALS were related to LV remodeling at 6-month follow-up and to adverse events. RESULTS Diabetes mellitus, GLS and PALS independently predicted LV remodeling. With multivariable Cox proportional hazards, diabetes mellitus, GLS and PALS were predictive of adverse clinical outcomes. However, PALS did not add significant incremental value beyond LV GLS in the prediction of LV remodeling (increase in area under the receiver-operator characteristic curve [AUC] 0.05, p = 0.24) and clinical events (even a decrease in AUC 0.03, p = 0.69). CONCLUSIONS Both GLS and PALS provide independent prognostic value for adverse LV remodeling and clinical outcomes after STEMI. However, the ability of the combination of PALS and GLS to predict LV remodeling and clinical outcomes may not be superior to that of a single indicator.Anatomic variations of the brachial plexus are common. Awareness of these variations is of paramount importance in clinical practice mainly in achieving best results in minimal invasive or surgical procedures. The aim of our study was to depict a case of a trifid lateral root origin of the medial nerve. This anatomical variation in the brachial plexus was encountered after dissection in upper extremities in a 90-year-old male cadaver.Polyethylene terephthalate (PET) is one of the most used polymeric materials in the health care sector mainly due to its advantages that include biocompatibility, high uniformity, mechanical strength and resistance against chemicals and/or abrasion. However, avoiding bacterial contamination on PET is still an unsolved challenge and two main strategies are being explored to overcome this drawback the anti-adhesive and biocidal modification of PET surface. While bacterial adhesion depends on several surface properties namely surface charge and energy, hydrophilicity and surface roughness, a biocidal effect can be obtained by antimicrobial compounds attached to the surface to inhibit the growth of bacteria (bacteriostatic) or kill bacteria (bactericidal). Therefore, it is well known that granting antibacterial properties to PET surface would be beneficial in the prevention of infectious diseases. Different modification methods have been reported for such purpose. This review addresses some of the strategies that have been attempted to prevent or reduce the bacterial contamination on PET surfaces, including functionalisation, grafting, topographical surface modification and coating. Those strategies, particularly the grafting method seems to be very promising for healthcare applications to prevent infectious diseases and the emergence of bacteria resistance.BACKGROUND Accumulating evidence demonstrated immune/inflammation-related implications of basophils in affecting tissue microenvironment that surrounded a tumor, and this study aimed to elucidate the clinical value of serum basophil count level. METHODS Between December 2007 and September 2013, 1029 patients diagnosed with stage I-III CRC in Fudan University Shanghai Cancer Center meeting the essential criteria were identified. The Kaplan-Meier method was used to construct the survival curves. Several Cox proportional hazard models were constructed to assess the prognostic factors. A simple predictor (CB classifier) was generated by combining serum basophil count and serum carcinoembryonic antigen (CEA) level which had long been accepted as the most important and reliable prognostic factor in CRC. RESULTS The preoperative basophils count less then  0.025*109/L was strongly associated with higher T stage, higher N stage, venous invasion, perineural invasion, elevated serum CEA level, and thus poor survival (P  less then  0.05). Moreover, multivariate Cox analysis showed that patients with low level of preoperative basophils count had an evidently poorer DFS [Hazard ratio (HR) = 2.197, 95% CI 1.868-2.585]. CONCLUSIONS As a common immune/inflammation-related biomarker available from the blood routine examination, low level of preoperative serum basophil count was associated with aggressive biology and indicated evidently poor survival. Preoperative serum basophil count would be a useful and simple marker for the management of CRC patients.The co-contamination of farmland soils with heavy metals and antibiotics from the application of livestock and poultry manures poses great threats to human health. Phytoremediation might be a good solution to this problem. A pot culture experiment was conducted to evaluate the remediation capacity of two ornamental hyperaccumulators, namely, Mirabilis jalapa L. and Tagetes patula L., in alkaline soils co-contaminated with cadmium (Cd) and tetracycline antibiotics (TCs). The growth of M. jalapa and T. patula was significantly influenced by the co-contaminated soil. In treatments with TCs alone, the growth of T. patula was promoted (p  less then  0.05), while that of M. jalapa was inhibited. [https://www.selleckchem.com/products/forskolin.html check details] In the C2T3 treatment with TCs and Cd combined, the biomass of T. patula and M. link2 jalapa decreased by 42.27% and 56.15% in roots and by 22.24% and 32.27% for in shoots, respectively, compared with those in the same treatment without TCs. The addition of TCs increased the accumulation of Cd in treatments with less than 15.0&nbsp;mg/kg Cd. In M. jalapa, the concentration of Cd increased by 4.64% and 39.69% in roots and by 30.33% and 71.71% in shoots, and that in T. patula increased by 74.66% and 11.03% in roots and by 15.36% and 17.58% in shoots, respectively, in two treatments with TCs compared with those in the treatments with Cd alone. However, the accumulated Cd amounts decreased from 36.25 to 31.91&nbsp;μg/pot and increased from 201.33 to 229.26&nbsp;μg/pot in C2T2 for M. jalapa and T. patula, respectively, compared with those in the treatments without TCs. The TC removal efficiencies of all treatments were above 99%, and the residual amounts of TC and OTC were higher than that of CTC. M. link3 jalapa and T. patula are promising hyperaccumulators that can be used for the remediation of alkaline soil co-contaminated with Cd and TCs.To evaluate the proportions of current cigarette smokers (CCS) and current narghile smokers (CNS) as well as previous cigarette smokers (PCS) and previous narghile smokers (PNS) and to assess smoking knowledge and attitudes toward supporting smoking ban or cessation among previous compared with current smokers. This cross-sectional study took place between May and December 2018, and enrolled a sample of 1598 exclusive cigarette smokers (ECS) and 2091 exclusive narghile smokers (ENS), representative of all Lebanese governorates. A questionnaire designed specifically for this study was used to collect data. Among ECS, 45.2% were CCS and 54.8% were PCS. Among ENS, 83.5% were CNS and 16.5% were PNS. Higher age (adjusted odds ratio (aOR) (95% confidence interval (CI)) = 1.02 (1.01; 1.03)), higher knowledge (1.05 (1.02; 1.08)), and attitude scores (1.11(1.09; 1.13)) were significantly associated with higher odds of being PCS. Higher age (1.02 (1.01; 1.03)), being employed (1.32 (1.004; 1.72)), higher knowledge (1.04 (1.02; 1.07)), and attitude scores (1.09 (1.07; 1.12)) were significantly associated with higher odds of being PNS. Previous smokers have higher knowledge and better attitude toward supporting smoking cessation compared with current smokers. A better knowledge along with effective interventions, might lead to a positive attitude toward supporting smoking ban or smoking cessation among the general population.Globally, odorant incidents are occurring at an increasing frequency, magnitude, and duration under the dual influences of eutrophication and climate change. However, the contribution of multiple ecotypes to odorant production in the complicated and dynamic lake ecosystems remains unclear. In this study, the odorants and environmental conditions in algae-dominated zones (ADZs) and macrophyte-dominated zones (MDZs) in Lake Taihu were identified and characterized. Results showed that the ADZs were characterized by an abundance of pigments and nutrients and low DO levels, while the MDZs were featured as high TOC/TN ratios and high DO levels. Most odorants in ADZs and several in MDZs exceeded the odorant threshold content. The dominant odorants were dimethyl disulfide (DMDS) and dimethyl trisulfide (DMTS), β-ionone and β-cyclocitral in ADZs, which were associated with the accumulation and decomposition of algal detritus. For MDZs, the dominant odorants were 2-methylisoborneol (2-MIB) and geosmin, which were at least partially attributed to the massive addition of bait in a traditional aquaculture area. In addition, the odorant concentration in the water of ADZs was approximately 3 to 21 times higher than that in MDZs, while in the benthic sediment, the odorant concentration in ADZs was approximately 2 to 3 orders of magnitude higher than in MDZs. This study highlights the production and accumulation of nuisance odorants in the benthic sediment of ADZs, indicating a risk of diffusion from the sediment to the water column. This was supported by the correlation of odorants in the water column with that in the sediment. The results of this study will be helpful for the management of different ecotypes suffering from nuisance odorants problems.Chlorotoluene rectification residual liquid (CRRL) from chlorotolune industry is hard to dispose of because of its high chlorine concentration, which poses high dioxin risk once it is subjected to incinerate. This research employed a chemical approach by using Williamson ether synthesis (WES) method for CRRL dechlorination. It shows that the sodium dosage, the ethanol dosage, and the ultrasonic time are the key factors in chlorine removal. The highest removal rate of chlorine was observed when the sodium dosage, the ethanol dosage, and the ultrasonic time were 0.35&nbsp;g&nbsp;mL-1, 0.8&nbsp;mL&nbsp;mL-1, and 15&nbsp;min, respectively. The further optimization tests indicate that the highest chlorine removal efficiency of 39.06% was observed when the ultrasonic time was 15&nbsp;min, the sodium dosage and the ethanol dosage were 0.5&nbsp;g&nbsp;mL-1 and 1.1&nbsp;mL&nbsp;mL-1, respectively. It suggests a feasible chlorine removal process for organic hazardous waste with high chlorine content before incineration.