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05) and one year (p&lt;0.05), postoperatively.<br /><br /> This study demonstrated that HPVP could achieve a lower cement leakage rate with similar operative time, lower VAS and ODI scores, as well as better kyphosis restoration and AR recovery at the 1-year follow-up than NPVP. HPVP is thus superior to NPVP in treating KD. Key Words Kyphosis, Cobb's angle, Cement leakage, Intervertebral stability, Surgical outcome, Kümmell disease, Vertebroplasty, Hyperextension position.<br /><br />This study demonstrated that HPVP could achieve a lower cement leakage rate with similar operative time, lower VAS and ODI scores, as well as better kyphosis restoration and AR recovery at the 1-year follow-up than NPVP. HPVP is thus superior to NPVP in treating KD. Key Words Kyphosis, Cobb's angle, Cement leakage, Intervertebral stability, Surgical outcome, Kümmell disease, Vertebroplasty, Hyperextension position.<br /><br /> To determine the predictive value of the delta neutrophil index (DNI) for acute pyelonephritis (APN), which increases in conditions of infection and inflammation.<br /><br /> Observational, comparative cross-sectional study.<br /><br /> Department of Urology, Kahramanmaraş Sütçü İmam University, Turkey, from December 2014 to November 2019.<br /><br /> The data of 205 patients, diagnosed with ureteral stone and urinary tract infection (UTI), were evaluated. For comparison, patients were categorised into two groups those with lower UTI (LUTI) and those with APN. Together with demographic data of patients and ureteral stone, DNI, C-reactive protein (CRP), white blood cell (WBC) and other biochemical parameters were analysed.<br /><br /> There were 165 patients (80.5%) in the LUTI group and 40 patients (19.5%) in the APN group. In univariate analysis, age (p=0.023), creatinine (p=0.001), PT/INR (p=0.007), WBC (p &lt;0.001), CRP (p=0.002) and DNI (p &lt;0.001) were identified as predictors of APN. In multivariate analysis, CRP (p=0.019) and DNI (p=0.009) were significantly associated with the predictors of APN. Cut-off values were 11.75 mm3 for WBC, 22.2 mg/dL for CRP, and 1.3% for DNI. DNI value was positively correlated with WBC and CRP (r=0.369 vs. [https://www.selleckchem.com/products/CP-690550.html Tofacitinib solubility dmso] 0.740 and p &lt;0.001, each).<br /><br /> As an infection marker that can be monitored with a complete blood count and does not require additional costs, DNI can be used as an early predictor of APN. Patients with a DNI value of &gt;1.3% should be considered for early intervention. Key Words Ureteral stone, Acute pyelonephritis, Delta neutrophil index, C-reactive protein, White blood cell.<br /><br />1.3% should be considered for early intervention. Key Words Ureteral stone, Acute pyelonephritis, Delta neutrophil index, C-reactive protein, White blood cell.<br /><br /> To compare recovery of eosinopenia, C-reactive protein (CRP) and procalcitonin levels in predicting the response to treatment in patients with cholangitis.<br /><br /> Descriptive, analytical study.<br /><br /> Department of Gastroenterology, Sakarya Training and Research Hospital, Turkey between September 2018 and February 2019.<br /><br /> Patients with cholangitis, who underwent endoscopic retrograde cholangiopancreatography (ERCP), were inducted. Those with choledocholic thiasis alone were considered controls. Eosinophil count above 100.5 cells/µL was the limit value accepted as improvement. ERCP repeat was decided according to eosinophil count below 100.5 and not clinically improving. Relationship between inflammatory markers such as CRP, procalcitonin and eosinopenia values in patients with stone-associated cholangitis was investigated.<br /><br /> The cholangitis group was comprised of 62 patients [mean age 67±14.57 years; 26 (41.9%) female], while control group was comprised of 57 patients [mean age 57.4±18.10 years; 39 (68.4%) females, plcitonin.<br /><br /> To compare two human leukocyte antigen (HLA) typing methods, namely sequence specific primers (SSP) and next generation sequencing (NGS) for alleles concordance Study Design Descriptive study.<br /><br /> Immunology department, Armed Forces Institute of Pathology, Rawalpindi, Pakistan, from December 2019 to May 2020.<br /><br /> A total of 48 subjects, including 30 males and 18 females, were typed by NGS at 7 loci, making a total of 672 types loci. SSP typing was done for 276 loci among these. Comparison was made at SSP level of low resolution. NGS typing was done with Illumina's MiSeq instrument using Omixon HLA holotype 7 loci kit and analysis done with HLA twin software. SSP typing was done with micro SSP kit from onelambda. Statistical analysis was done using statistical package for social sciences (SPSS) version 24.0.<br /><br /> Among the 672 NGS types loci and 276 SSP types loci, there were mismatches at one B locus and one C locus, whereby NGS computed HLA-B*5801 and HLA-C*1202 while SSP detected HLA-B*57 and HLA-C*05, respectivimplementation in 3rd world countries. Key Words Human leukocyte antigen, Next generation sequencing, High resolution.<br /><br /> To evaluate the mechanical properties of the tissues and muscles in the anal region with the shearwave elastography for anal fissure etiology.<br /><br /> Descriptive study.<br /><br /> Adana City Training and Research Hospital, Turkey, from March2019 to March 2020.<br /><br /> In this study, 30 patients (fissure group), who were diagnosed with anal fissure in the outpatient clinic; and 20 patients (control group), who did not have any problem in anal examination were included. The anorectal tissues and muscles mechanical properties(elasticity,compliance and stiffness) were compared with the shear wave elastography values.Fissure area,internal anal sphincter,external anal sphincter and levator ani muscles elastographic measurements was performed with 5-18 MHzin lithotomy position, at rest and with Valsalva maneuver.<br /><br /> In elastographic measurement of fissure area (fissure) and normal anorectal tissue (control, AFE); control group values were significantly higher than the fissure group values (p&lt;0.001, and padj &lt;0.001, respectively)phy, Shear wave elastography, Anal sphincter, Tissue elasticity, Tissue stiffness.<br /><br />11kPa for LAM,respectively. Conclusıon In anal fissure disease, tissues mechanical properties measured by shear wave elastography showed increased tissue stiffness, which may be added to etiology of this disease. Key Words Anal fissure, Ultrasonography, Shear wave elastography, Anal sphincter, Tissue elasticity, Tissue stiffness.