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we have previously demonstrated, DNA methylation encapsulates lifetime exposure to blast. The current data support previous findings and recapitulate transcriptional regulatory alterations in genes involved in sleep, auditory function, and pain. These data uncovered novel epigenetic and transcriptional regulatory mechanism underlying the etiological basis of these symptoms.A stroke prediction model based on the Prediction for Atherosclerotic Cardiovascular Disease Risk in China (China-PAR) project was developed. We compared its predictive ability with the revised Framingham Stroke Risk Score (R-FSRS) for 5-year stroke incidence in a community cohort of Chinese adults, namely the Beijing Longitudinal Study of Aging (BLSA). Calibration, discrimination, and recalibration were used to compare the predictive ability between the two prediction models. Category-less net reclassification improvement (NRI) and integrated discrimination improvement (IDI) values were also assessed. During a mean follow-up duration of 5.1 years, 106 incidents of fatal or non-fatal strokes occurred among 1,203 participants aged 55-84 years. The R-FSRS applied to our cohort underestimated the 5-year risk for stroke in men and women. China-PAR performed better than the R-FSRS in terms of calibration (men, R-FSRS χ2-value 144.2 [P less then 0.001], China-PAR 10.4 [P = 0.238]; women, R-FSRS 280.1 [P less then 0.001], China-PAR 12.5 [P = 0.129]). In terms of discrimination, R-FSRS and China-PAR models performed modestly in our cohort (C-statistic 0.603 [95% CI 0.560-0.644] for men using China-PAR and 0.568 [95% CI 0.524-0.610] using the R-FSRS; the corresponding numbers for women were 0.602 [95% CI 0.564-0.639] and 0.575 [95% CI 0.537-0.613). The recalibrated China-PAR model significantly improved the discrimination in C statistics and produced higher category-less NRI and IDI for stroke incidence than the R-FSRS. Although China-PAR fairly estimated stroke risk in our cohort, it did not sufficiently identify adults at high risk of stroke. Caution would be exercised by practitioners in applying the original China-PAR to Chinese older adults. Further studies are needed to develop an adequate prediction model based on the recalibrated China-PAR or to find new risk markers which could upgrade this model.[This corrects the article DOI 10.3389/fpsyg.2020.01975.].[This corrects the article DOI 10.3389/fpsyg.2020.588604.].[This corrects the article DOI 10.3389/fpsyg.2019.02611.].<br /><br /> Besides the evident positive effect on body development, physical activity has proven to boost executive functions, especially if the exercises are enriched with cognitive stimuli. Previous studies have shown that introducing challenging exercises in the physical activity routine can also enhance motivation. Therefore, enriching a physical education program with cognitively challenging exercises may also foster children's motivation during physical education classes, where the motivation is high at the beginning of the school year and low at the end of it. Therefore, the purpose of this paper is to test if a sport program enriched by cognitive stimuli may improve kids' motivation or take them out from a state of amotivation along the school year.<br /><br /> A sample of 342 school children (203 boys, 139 girls) took part in the study. Participants were asked to complete a battery of motivation and perceived social support questionnaires before and after they completed the ESA Program, a sport program enriched with cognitive stimuli. [https://www.selleckchem.com/products/Estrone.html selleck kinase inhibitor] Moreover, parents of these children attended four seminars about the importance of supporting children for the practice of regular physical activity (PA). A control group consisting of children that attended the ordinary physical education school class was also included.<br /><br /> A repeated measures MANOVA model showed that the ESA Program was able to improve children's general motivation, in particular the intrinsic motivation. The program was not effective in social support, but, independently from the group, the family social support in sports activities decreased for females.<br /><br /> Apart from cognitive improvement, the ESA Program can have beneficial effects on children's sports motivation in physical education, but not on perceived social support.<br /><br />Apart from cognitive improvement, the ESA Program can have beneficial effects on children's sports motivation in physical education, but not on perceived social support.Introduction The impulsivity, sensation-seeking, and drug use variables, in addition to being closely related, have repercussions on peer conflict and violence in schools. Objective The purpose of this study was to analyze the relationship between impulsivity, sensation-seeking, and drug use in aggressors and victims of violence. Methods The study design was cross-sectional and observational. The study sample was made up of 822 students aged 13-18 who had completed an ad hoc questionnaire, the State Impulsivity Scale and the Sensation-Seeking Scale. Results The results showed that the aggressors had high levels of gratification, automatism, attentional factor, disinhibition, and susceptibility to boredom and used alcohol and/or tobacco. Conclusion The design of an effective education intervention for reducing risk behaviors related to violence must focus on these variables.The paper presents the potential benefits and conflicts of the encounter between Jewish ultra-orthodox (UO) children - belonging to a closed and segregated group - and art therapy - with its cultural, Western, secular, and professional characteristics. The paper describes the complex interface between the therapeutic use of art as a form of free expression and religious commandments and restrictions. The dialogue between art, therapy, and cultural religious boundaries is described through a case study of an 8-year-old UO boy and a secular female art therapist. Issues such as self-expression, gender roles, and identity exploration are discussed, emphasizing the unique characteristics, benefits, and conflicts of such an encounter.[This corrects the article DOI 10.3389/fpsyg.2020.00839.].Cognitive impairment is a significant risk factor for hazardous driving among older drivers with Alzheimer's dementia, but little is known about how the driving behavior of mildly symptomatic compares with those in the preclinical, asymptomatic phase of Alzheimer's disease (AD). This study utilized two in-car technologies to characterize driving behavior in symptomatic and preclinical AD. The goals of this pilot study were to (1) describe unsafe driving behaviors in individuals with symptomatic early AD using G-force triggered video capture and (2) compare the driving habits of these symptomatic AD drivers to two groups of cognitively normal drivers, those with and those without evidence of cerebral amyloidosis (CN/A+ and CN/A-) using a global positioning system (GPS) datalogger. Thirty-three drivers (aged 60+ years) were studied over 3 months. G-force triggered video events captured instances of near-misses/collisions, traffic violations, risky driver conduct, and driving fundamentals. GPS data were sampled vers with preclinical AD may compensate for early, subtle cognitive changes by driving more slowly and cautiously than healthy older drivers or those with cognitive impairment. Self-regulatory changes in driving behavior appear to occur in the preclinical phase of AD, but safety concerns may not arise until symptoms of cognitive impairment emerge and the ability to self-monitor declines.Research on the relationship between work stress and employee creativity has been mixed. This study on 823 female attorneys in China identifies employee creative self-efficacy and employees' value of Zhongyong as moderators in this relationship. In this study, work stress is assessed by the perceived work uncertainty brought on by the COVID-19 pandemic. Our study found that although Zhongyong, which involves an employee's ambidextrous thinking, can be helpful for employee creativity, low levels of Zhongyong are better for employee creativity in an uncertain context such as the COVID-19 pandemic, due to the fact that high levels of Zhongyong result in an overemphasis on compromise and giving in when times are uncertain. Instead, low levels of Zhongyong will decrease employees' concern about others' acceptance in an uncertain environment. In addition, creative self-efficacy motivates employees to engage in creative efforts during times of work uncertainty. In sum, this study found that employee perceived work uncertainty brought on by COVID-19 enhances employee creativity when an employee's value of Zhongyong is low and creative self-efficacy is high.Recent experimental studies suggest that preverbal infants are able to evaluate agents on the basis of their distributive actions. Here we asked whether such evaluations are based on infants' understanding of the distributors' intentions, or only the outcome of their actions. Ten-month-old infants observed animated movies of unequal resource allocations by distributors who attempted but failed to distribute resources equally or unequally between two individuals. We found that infants attended longer to the test event showing a third agent approaching a distributor who was unable to make an unequal distribution, compared to the test event where the third agent approached a distributor who was unable to make an equal distribution of resources. Our results suggest that infants' ability to encode distributive actions goes beyond an analysis of the outcome of these actions, by including the intentions of the distributors whose actions lead to these outcomes.This quasi-experimental study examined training in two types of reading strategies self-generated questions either connecting to prior knowledge (Extra-Text) or connecting between the text's parts (Within-Text). Immediate and long-term effects were assessed on ninth graders' science text comprehension, versus an untrained control group. The three student groups (N = 193) received the same study unit of scientific texts and accompanying tasks, either with/without training in self-generated questioning. PISA-based science literacy assessments (phenomenon identification, scientific explanation, and evidence utilization) were collected at baseline, immediately after intervention, and at 4-month follow-up. Results from both short- and long-term assessments indicated that those learners trained to generate questions about within-text connections reached significantly higher science text comprehension achievements than the other two groups - students trained to generate questions connecting to their prior knowledge and control students who received no support for generating questions. Findings may contribute to the design of support methods and teaching strategies for promoting literacy in general and scientific literacy in particular.The so-called traditional motor games are group situations that function like small-scale societies, full of emotionally rich vicissitudes and proper objectives, alliances, and antagonisms. Traditional games have certainly been the object of many dispersed, really interesting studies, but no general conception of them, based on a scientifically supported methodological approach, has been developed so far. How do these games work? Does their development depend on sheer chance? Does it respond to any underlying structures? Is this development anyhow related to the socio-emotional dynamics of the group of players? As a whole, do these games, so different from each other, have any common characteristics that generate similar effects on the personality of the players? In the end, is what we know about a given game comparable and generalisable to any other one?