Zobrazení zdroje stránky Berthelsenkilgore8425

The compositional distributions of MPs and levels of carcinogenic and toxic metals and phthalate esters are presented. The dataset could be used for the evaluation of ecological risk associated with PAEs in the marine ecosystems.RNA-Seq transcriptome data from twenty Siberian sturgeon gonads at different developmental stages is described ten undifferentiated gonads, six gonads of immature males and four gonads from immature females. Siberian sturgeon, Acipenser baerii, is long-lived, late-maturing fish farmed in 50 countries but its production remains on a craftsman scale when compared to industrial species. Sturgeon genetic and physiological studies are less developed than for industrial fish. The data presented hereafter enables fundamental studies on the regulatory mechanisms of sturgeon gonad development, which can further be applied both in aquaculture and in fundamental research.Aspidistra is a large genus of herbaceous plants with more than 130 species growing in tropical forests of SE Asia and specially diversified in southern China and northern Vietnam. The genus is characterized by its evergreen understorey habitats with flowers set at ground level and more or less hidden in litter material. Aspidistra fenghuangensis is a species currently only known from central China. In recent years, number of species in this genus has been greatly increased. However, the high throughput sequencing data have never been reported in this genus. Here, we sequenced the transcriptome of A. fenghuangensis obtained from young leaves using the Illumina HiSeq2000 with 9.15Gb of clean data. Because of the absence of a reference-grade genome in the genus, a de novo assembly of the transcriptome data with full annotation have been carried out. This data is accessible via NCBI BioProject (PRJNA608213).There are over a hundred genotypes of Phaseolus vulgaris L. grown and consumed in Tanzania. Currently, identification of bean genotypes containing high seed iron and zinc contents has been the focus globally for common bean iron and zinc biofortification. Diversity in seed iron and zinc contents were investigated in 99 bean genotypes grown in Tanzania to identify high seed iron and zinc-containing genotypes for use in iron and zinc biofortification. Flour obtained by grinding seeds of each bean genotypes was used in the determination of iron and zinc concentrations. Data were subjected to analysis of variance (ANOVA) to determine significant differences among common bean genotypes in terms of seed iron and zinc contents. Additive main effects and multiplicative interaction (AMMI) and genotype plus genotype by environment interaction (GGE) were conducted to determine stability and adaptation across sites (TARI-Selian, SUA, and TARI-Uyole) of bean genotypes in terms of seed iron and zinc contents. Data in this data article show that some landraces had high seed iron and zinc contents compared to release varieties thus can be used for iron and zinc genetic biofortification in common beans breeding programs. For more explanation of the data presented in this data article, please follow the related research article "Environmental and genotypes influence on seed iron and zinc levels of landraces and improved varieties of common bean (Phaseolus vulgaris L.) in Tanzania" [1].Since its first outbreak in 2007 in the Pacific (Yap islands and Federal States of Micronesia), Zika virus has gradually and recently spread to the Americas in 2015. The neurotropic character of the virus was first noted during this outbreak in Brazil in 2015. Increasing number of infants born with microcephaly and other congenital deformities were identified through studies that have highlighted the importance of prevention of transmission of Zika virus in pregnant women. Long-term outcomes in infants born with this infection are now better understood than at the time of onset of this outbreak. Topics covered in this review include the history, modes of transmission, diagnosis of suspected cases, pathophysiology, complications, and prevention of Zika virus infection.Adolescence and young adulthood can be particularly daunting for those with mental health concerns. In one Canadian city, a community-based drop-in psychosocial mental health center (Center) was designed specifically for youth who self-identified as struggling with mental health issues. The purpose of this study was to identify the features of the program that promoted or discouraged engagement. Narrative inquiry was used to guide the project. One-on-one interviews were conducted with 10 Center users. Four major categories were identified (a) Reasons for Coming Motivated to Work on Goals; (b) Facilitators of Engagement and Beyond; (c) Challenges to Engagement; and (d) Benefits of Engaging Finding My Way. These categories were further delineated into themes. All participants had experienced trauma, and the Center assisted them in their coping. The researchers believe that to aid recovery, agencies working with this population need to use trauma-informed and healing-centered engagement.There is a called-for shift to an upstream provision of palliative care as an overall care approach within a health equity perspective. Our research explored how nurses in psychiatry engage with aging patients and mortality to discern enactment of ethical dimensions of care. Drawing from tenets of interpretative phenomenological analysis, forensic and geriatric psychiatry registered nurses working at a mental health facility in eastern Ontario completed interviews for analysis. Nurses engaged with mortality through a process of recognition and through the affirmation of their values. The affirmed values are aligned with the palliative care approach and within an ethics of finitude lens in that their enactment is partly premised on the recognition of patients' accumulated losses related to human facticities (social, temporal, mortal). This research underscores preliminary insights on a process identifying care practices aligned with the palliative approach and possibilities for expanding upon an ethics of finitude lens.Research objective Using a multilevel framework, the study examines the association of socioeconomic characteristics of the individual and the community with all-cause 30-day readmission risks for patients hospitalized with a principal diagnosis of opioid use disorder (OUD). Study design The study uses hospital discharge data of adult (18+) patients in 5 US states for 2014 from the Healthcare Cost and Utilization Project of the Agency for Healthcare Research and Quality, linked to community and hospital characteristics using data from Health Resources and Services Administration and American Hospital Association, respectively. A multilevel logistic regression model is applied on data pooled over 5 states adjusting for patient, hospital, and community characteristics. Principal findings Higher primary care access, as measured by density of primary care providers, is associated with reduced readmission risks among patients with OUD. [https://www.selleckchem.com/products/lipopolysaccharides.html Lipopolysaccharides] Medicare is associated with the highest readmission risk (odds ratio [OR] = 2.0, P less then .01) compared to private coverage, while Medicaid coverage is also associated with elevated risk (OR = 1.71, P less then .01). Being self-pay or covered by other payers carried a similar risk to private coverage. Urban patients had higher readmission rates than rural patients. Conclusions Patients' risk of readmission following hospitalization for OUD varies according to availability of primary care providers, expected payer, and geographic location. Understanding which patients are most at risk may allow policy makers to design interventions to prevent readmissions and improve patient outcomes. Future studies may wish to focus on understanding when a decreased readmission rate represents better patient outcomes and when it represents difficulty accessing health care.Orbital actinomycosis is an unusual clinical manifestation of orbital infection caused by Actinomyces species. Herein we report a case of orbital actinomycosis in a 67-year-old woman with recurrent swelling and erythema around her left eye with an orbital mass initially thought to be a meningioma.Background The largest health care-associated infection outbreak in the United States occurred during 2012-2013. Following injection of contaminated methylprednisolone, 753 patients developed infection with a dematiaceous mold, Exserohilum rostratum. The long-term outcomes of these infections have not been described. Methods This retrospective cohort study of 440 of a total of 753 patients with proven or probable Exserohilum infection evaluated clinical and radiographic findings, antifungal therapy and associated adverse effects, and outcomes at 6 weeks, 3, 6, 9, and 12 months after diagnosis. Patients were grouped into 4 disease categories meningitis with/without stroke, spinal or paraspinal infections, meningitis/stroke plus spinal/paraspinal infections, and osteoarticular infections. Results Among the 440 patients, 223 (51%) had spinal/paraspinal infection, 82 (19%) meningitis/stroke, 123 (28%) both, and 12 (3%) osteoarticular infection. Of 82 patients with meningitis/stroke, 18 (22%) died; among those surviving, 87% were cured at 12 months. Only 7 (3%) of 223 patients with spinal/paraspinal infection died, but at 12 months, 68% had persistent or worsening pain and only 47% were cured. For the 123 patients with both meningitis/stroke and spinal/paraspinal infection, 10 (8%) died, pain persisted in 72%, and 52% were cured at 12 months. Only 37% of those with osteoarticular infection were cured at 12 months. Adverse events from antifungal therapy were noted at 6 weeks in 71% of patients on voriconazole and 81% on amphotericin B. Conclusions Fungal infections related to contaminated methylprednisolone injections culminated in death in 8% of patients. Persistent pain and disability were seen at 12 months in most patients with spinal/paraspinal infections.Background Drug-resistant cytomegalovirus (CMV) infection has been increasingly recognized. However, there are limited data in pediatric patients. In this study, the prevalence and factors associated with CMV infection with UL97 mutations in pediatric patients treated with ganciclovir but not responding to treatment were evaluated. Methods This retrospective study was conducted from January 2013 to December 2017. All patients who were suspected of having ganciclovir-resistant CMV infection and had never had ganciclovir prophylaxis were included. Genotypic assay for UL97 mutations in codons 460 and 520 conferring ganciclovir resistance was performed. Factors associated with the presence of UL97 mutations were analyzed. Results Of 34 patients included, 10 patients (29.4%) had a genotypically confirmed UL97 mutation. The median age (interquartile range [IQR]) was 3 (0.85-8.68) years. Ganciclovir resistance was tested at a median time (IQR) of 22.5 (14.3-31) days after initiation of ganciclovir. All resistant isolates harbored a UL97 mutation in codon 460. Compared with patients infected with CMV without UL97 mutation, those infected with UL97 mutation strains were younger (median age [IQR], 3.02 [0.85-8.68] vs 10.45 [2.7-16.4] years) and had a higher maximum viral load (median [IQR], 5.06 [4.74-6.05] vs 4.42 [4.03-4.87] copies/mL). Six of 10 (60%) patients were successfully treated with high-dose ganciclovir (7.5 mg/kg twice daily). Conclusions UL97 mutation ganciclovir-resistant CMV infection was not uncommon in the pediatric population. Screening for this mutation should be considered in patients experiencing virological worsening while ganciclovir is given, even if patients have not previously received ganciclovir prophylaxis.