Zobrazení zdroje stránky Banghelbo1582

0 PL license.In the past, 2-naphthylamine (2-NA) was used for the production of azo dyes, as an antioxidant in the cable industry and in the rubber industry. Despite the fact that 2-NA is not produced on an industrial scale, it is still used in small quantities as a model bladder carcinogen in laboratories, and also for sewage control, water analysis and oxytocinase assays. [https://www.selleckchem.com/products/PP242.html selleck chemical] In addition, it is detected in the air in coke ovens, where it is formed as one of the pyrolysis products. The main aim of this work is to provide an actual literature review for health risk assessments related to 2-NA which is still used in laboratories. Occupational exposure to 2-NA is important for the respiratory tract, mucous membranes and the skin, and, to a lesser extent, for absorption from the gastrointestinal tract. It is absorbed into the body through the skin and by inhalation, and then undergoes metabolic changes. Most of the absorbed 2-NA dose is excreted in the urine, in the form of metabolites, metabolites conjugated to acids, and even in an unchanged form. Based on literature data, the effects of 2-NA toxicity in sub-chronic and chronic exposure include contact dermatitis, chronic cystitis and bladder cancer. The authors have concluded that it is recommended to determine the occupational exposure limit which will allow preparing the exposure assessment of people at work. This work is available in Open Access model and licensed under a CC BY-NC 3.0 PL license.in English, Polish Na podstawie wyników wielu badań i analiz prowadzonych w różnych krajach potwierdzono, że obturacyjny bezdech senny (OBS) negatywnie wpływa na zdolności psychofizyczne kierowców. Dlatego w Dyrektywie Unii Europejskiej z dnia 1 lipca 2014 r. OBS został uznany za jeden z najważniejszych czynników ryzyka wypadków samochodowych. Realizacja postanowień tej dyrektywy w państwach członkowskich ma przyczynić się do jego ograniczenia. Wynikiem jej implementacji w Polsce jest rozporządzenie Ministra Zdrowia z dnia 23 grudnia 2015 r. zmieniające rozporządzenie w sprawie badań lekarskich osób ubiegających się o uprawnienia do kierowania pojazdami i kierowców. Mimo że w załączniku nr 2 tego rozporządzenia podano szczegółowe warunki badania lekarskiego w przypadku podejrzenia OBS, nie uregulowano ani nie wyjaśniono kwestii narzędzi i sposobu pozwalających na powzięcie w przypadku badanego pacjenta podejrzenia umiarkowanej lub ciężkiej postaci choroby. Dlatego konieczne było opracowanie dla lekarzy uprawnionych do badań lekarskich kierowców i osób ubiegających się o prawo jazdy standardów postępowania w przypadku podejrzenia występowania OBS. W artykule przedstawiono usprawniający proces orzeczniczy algorytm postępowania, który został opracowany przez Polskie Towarzystwo Medycyny Pracy, Polskie Towarzystwo Chorób Płuc, Instytut Medycyny Pracy w Łodzi i Polskie Towarzystwo Badań nad Snem.Extension-block pinning is a popular surgical treatment method for mallet fractures but is associated with several pitfalls. Transfixation Kirschner wires used in the extension-block pinning technique may cause iatrogenic nail bed injury, bone fragment rotation, chondral damage, or osteoarthritis. The objective of this study was to determine the result of the delta wiring technique in mallet fractures with fracture fragment involving more than one-third of the distal phalanx articular surface. The authors are reporting 5 cases of mallet fractures treated with delta wiring technique with good functional and radiologic outcomes. Radiologic outcomes were evaluated on the basis of postoperative and follow-up x-rays and functional outcomes were evaluated using Crawford's criteria. Five patients (4 males, 1 female) with a mean age of 26.8 years (range, 20 to 33 y) were included. The mean time between the injury and surgery was 5 days (range, 3 to 7 d), and the mean follow-up period was 8.6 months (range, 8 to 10 mo). Radiographic bone union was achieved in all patients within an average of 6.4 weeks (range, 6 to 7 wk). At the final follow-up, the distal interphalangeal joint had an average degree of flexion of 73 degrees (range, 70 to 75 degrees) and an average extension deficit of 5.40 (range, 0 to 8 degrees). According to Crawford's criteria, 1 patient had excellent results and 4 patients had good results. No patient reported pain at the final follow-up with a visual analog scale score mean of 0.6 (range, 0 to 2). Satisfactory clinical and radiologic outcomes were obtained with the delta wiring technique. Future prospective and randomized studies are justified to confirm the efficacy of this technique.PURPOSE The purpose of this study was to demonstrate how to tension tendon and ligament repairs or reconstructions to bone by using an oblique screw-post. A controlled experiment simulating this repair technique is reported, followed by 5 case examples. METHODS A wood frame model was used to test 5 initial exposed screw lengths (4, 8, 12, 16, 20 mm) and 5 screw angles [90 (perpendicular to wood plane), 75, 60, 45, 30 degrees]. A spring-based force gauge was tied to the exposed 3.5 mm cortical screw with a washer using a #2 nonabsorbable braided suture, and the screw was fully advanced. System lengths were measured before and after advancement using digital calipers. Screw angles were measured with a protractor. Analysis of variance with post hoc paired t tests was performed to compare changes in system length with different initial exposed screw length and screw angle. RESULTS Greater changes in system length was achieved with decreasing screw angle and increasing initial exposed length (P less then 0.05). A maximum change in system length of 12.4 mm (SD=0.4 mm) was achieved with a 45-degree screw with 20 mm initial exposed length (P less then 0.05). Five case examples where a screw-post was used to repair tendons and ligaments in the upper extremity are described. CONCLUSIONS An oblique screw-post can advance a tendon or ligament repair to bone. This can result in increased tension of the repaired structure, potentially providing a better repair or greater joint stability.